Breast Cancer Prevention Evista can use Osteoporosi drugs, there are two types of drugs have been officially approved by the Food and Drug Administration to help protect women at high risk of breast cancer tamoxifen (nolvadex) and raloxifene (Evista).
Studies that examine the influence of tamoxifen and raloxifene, tamoxifen and raloxifene showed that can reduce breast cancer incidence in a similar way. When tamoxifen and raloxifene increase women’s risk for blood clots, a smaller increase was observed with raloxifene. raloxifene is also associated with a lower risk of cervical cancer and hysterectomy for reasons that are not cancer than tamoxifen. the conclusion that tamoxifen is more effective than raloxifene in preventing the development of non-invasive early cancer.
Evista
Evista is currently used by around half a million women in the United States to prevent and treat osteoporosis, or thinning bones. Previous researchers have observed lower levels of breast cancer in women taking Evista than the general population.
Drug Evista (raloxifene) is a huge benefit to postmenopausal women at high risk of breast cancer.
Second SERM raloxifene is approved by the FDA. This drug is approved for use in preventing osteoporosis in women after menopause. The data show that raloxifene, like tamoxifen, can reduce the possible development of breast cancer in women at high risk. Unlike tamoxifen, raloxifene does not stimulate the cells of the uterus, Evista seems to carry less risk of side effects, with lower rates of cervical cancer and clotting problems seen in women receiving tamoxifen, Evista.
Note the data from the effects of raloxifene in women before menopause is not available, and is a potential teratogen, which means that raloxifene can cause damage to the developing fetus. Therefore, limiting the use of raloxifene in women after menopause and is not recommended for use on pregnant women aged children.
Tamoxifen
Tamoxifen has actually long been used to help fight breast cancer. In 1998, the FDA approved tamoxifen for use by women who do not have a high risk of breast cancer but disease.
Several characteristics of breast cancer cells sensitive to estrogen, which means they have what is called estrogen receptor or estrogen-sensitive cells and requires estrogen stimulation to grow and divide. But the estrogen receptor have committed themselves to the cancer cells to stimulate them. Estrogen receptor binding is the same as the key into the Keyhole. tamoxifen stop the activity of estrogen on cancer cells with receptor occupation, thus preventing estrogen from binding to the receptor itself. With the help of the cancer cells of estrogen-sensitive cells, stopping the estrogen growth and multiplication of these cells. Tamoxifen is given in larger doses or higher might also have an ability that can cause cell death of breast cancer cells that are not estrogen sensitive.
Tamoxifen has been used to treat cancer early-stage breast cancer and that continues. This drug has proven useful in women who had cancer in one breast in reducing the likelihood of breast cancer in both.
Tamoxifen behaves like the element of anti-estrogen on breast tissue, he worked as a weak estrogen in the bone. And, tamoxifen has some benefit in preventing fracture / broken bones due to osteoporosis in women who have menopause.
Tamoxifen also reduced-Cysts Cysts (Cyst) and bump-bump (lump) in breast-breast, especially in young women. Cysts-cysts and lumps, bumps make early detection with fewer exams andmammograms, breast mammogram easier. Use of these drugs only in extreme situations and not using approved.
Tamoxifen showed decreased risk of breast cancer, non-invasive carcinoma (lobular carcinoma in situ and ductal in situ), but no reduction in risk for the condition with Evista.
Mastectomy and breast cancer prevention
What are your options?
Prevention or prophylactic mastectomy is the removal of one or both breasts, which operate on women who have a high risk of developing breast cancer. Research has shown that this technique reduces the possibility of a woman developing breast cancer up to 90%. Because a small amount of breast tissue may be left in the chest wall, armpit, or even in the stomach after a mastectomy, it is impossible to totally prevent the development of breast cancer by prophylactic mastectomy. The women often opt for breast reconstruction surgery. This is very important for a woman considering preventive mastectomy to have an honest discussion with your doctor about the risks of cancer, treatment options available, and the complications and implications of potential operations before making a decision.
Risks and side effects of tamoxifen
Tamoxifen is one of the risk of cervical cancer development. but the risk of cervical cancer as a whole is very small, in the trial NSABP-P1, more women receiving tamoxifen developed cancer of the uterus in women who received placebo.
In women aged above 50 years who received tamoxifen slightly increased risk for developing blood clots in blood vessels in the leg veins. These blood clots can sometimes come and run, causing a blockage in the blood vessels in the lungs, called pulmonary embolism. pulmonary embolism symptoms are shortness of breath, chest pain, and sometimes shock. Some studies also reported an increased risk of stroke in patients receiving tamoxifen.
In addition to side effects of tamoxifen, including weight loss, (hot hot flashes), irregular menstruation comes, vaginal dryness, and a small increase in risk of cataract, cataract. effects – this side effect depends on the age group being studied.
